The impact of innovative food ingredients on the human gut microbiome and health (WARREN_Q26CASE)

This project offers the opportunity to develop the next generation of microbiome targeted food ingredients. Working in collaboration between Quadram Institute and ADM, one of the worlds largest food ingredient suppliers, this PhD program will explore the impact of novel milling technologies on microbial accessibility of carbohydrates in food ingredients. Using cutting edge microbiome modelling techniques and bioinformatics approaches the studentship will explore the impact of these novel ingredients on gut microbiome composition and function. Using the latest in gut microbiome lab-based models and culture methods, the studentship will explore microbial dynamics, microbe carbohydrate degradation pathways and microbial binding to substrates. These findings will be placed into the context of human physiology looking at the impact on glycaemic responses and gut hormone signalling, e.g. GLP-1 and PYY, using advanced cell culture models. The partnership with ADM will give the student the opportunity for insights into how cutting edge research findings are translated into real world impact within a large multinational company.