Recruitment to the NRPDTP and iCASE programmes are now open. The deadline for applications is the 27th November 2017.

02 / 10 / 2017

Trans-generational inheritance of environmental information using regulation of long non-coding RNA. (PENFIELD_J18DTP1)

how to apply

Seeds are now understood to be highly plastic in their development and behaviour depending on environmental signals that control their development, particularly temperature. Crucially, temperature signals are not just perceived by seeds themselves but also by the mother plant, and the mother has major influences on seed development. We have shown that the mother plant has a memory of environmental temperature stretching back several weeks that controls reproductive development leading to seed dormancy. This memory is carried by a key gene known as FLOWERING LOCUS C (FLC) which can form epigenetic memories of past temperature experience. This project will investigate the mechanism by which the mother sends temperature information to FLC, using a mechanism involving regulation of non-coding RNAs transcribed at the FLC locus. The work will involve advanced training in plant molecular biology including epigenetics, epigenomics, use of reporter genes and microscopy to examine how temperature information is inherited into seeds. The successful applicant will join a large and well-funded research team with access to state-of-the-art facilities and world-leading expertise in plant reproductive biology.